METHOD OF DIFFERENTIAL DIAGNOSTICS OF PANCREATIC CANCER AND CHRONIC PANCREATITIS

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to gastroenterology, and can be applied in differential diagnostics of pancreatic cancer and chronic pancreatitis (CP) during initial visit to doctor with suspected pathology of pancreas. Activity of blood serum enzymes and the following parameters are determined: age, presence or absence of: yellowing of the skin, stones in Wirsung duct lumen, its tortuosity, pancreatoliths and cysts in parenchyma of pancreas, formations in liver, regional lymphadenopathy and involvement in pathological process of vessels in projection of pancreatoduodenal zone by USE data; erosions and lymphangiectasias in duodenum by FEGDS data. Biochemical indices are determined: levels of total bilirubin, triglicerides, C-peptide, tumour marker CA-19-9; ultrasonic indices: pancreas dimensions, its echogenicity, thickness of choledoch walls, its length, character of its content, gall bladder dimensions. After that, each sign is given corresponding point from table No 1, presented in description, obtained points are summed up. If point sum is +20 and more, chronic pancreatitis is diagnosed, if point sum is -13 and lower, pancreatic cancer is diagnosed, intermediate value of point sum "-12 - +19" is estimated as uncertain diagnosis.;EFFECT: method makes it possible to increase accuracy of differential diagnostics and possibility of application in clinical practice.;7 tbl, 6 ex