METHOD OF CHOOSING THERAPEUTIC APPROACH IN MENSTRUAL DISORDERS IN ADOLESCENT GIRLS WITH OVERWEIGHT

摘要

FIELD: medicine.;SUBSTANCE: in adolescent female patients with overweight suffering menstrual disorders of oligomenorrhea or amenorrhea type are examined for a body weight index (BWI) and blood serum leptin level measured by enzyme immunoassay. And if the BWI of the patient exceeds 25.0 kg/m², and the leptin level is less than 32.52 ng/ml, diet therapy and graduated physical activity are prescribed. The leptin level 32.52 ng/ml and higher in the patient requires additional glucose tolerance test to a common technique to detect insulin resistance. If observing insulin resistance, the complex treatment includes the preparations to provide higher peripheral tissue sensitivity (sensitisers) to insulin. The absence of insulin resistance enables to prescribe the therapy of combined oral contraceptives with drospirenone.;EFFECT: method allows prescribing well-timed adequate therapy for treating said disease and evaluating the efficacy of the performed therapy.;3 ex