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METHOD FOR PREDICTION OF CLINICAL EFFECT OF INHALATION GLUCOCORTICORTICOSTEROID APPLICATION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

机译:预测吸入性糖皮质激素治疗慢性阻塞性肺疾病患者的临床效果的方法

摘要

FIELD: medicine.;SUBSTANCE: haemoglobin concentration in patient's peripheral blood, a systolic pressure value of a pulmonary artery, and an end-diastolic volume of a right ventricle of heart are evaluated. Then the value F is calculated by formula: F=175-27.3×RVt-4.35×SPPA+0.5×H, where H is the peripheral blood haemoglobin concentration, g/l; RVt is the end-diastolic volume of the right ventricle of heart, cm; SPPA is the systolic pressure value of the pulmonary artery, mm Hg. If the value F0 is observed, a positive clinical effect is predicted, and the value F 0 means a negative clinical effect or its absence.;EFFECT: application of the method allows prescribing the IGCSs only to those patients showing the positive clinical effect to be reached, promoting the improvement of medical aid quality to the COPD patient, and reduced undesired steroid load on the patient.;2 ex
机译:领域:药物;对象:评价患者外周血中的血红蛋白浓度,肺动脉的收缩压值和心脏右心室的舒张末期容积。然后,通过以下公式计算值F:F = 175-27.3×RVt-4.35×SPPA + 0.5×H,其中H是外周血血红蛋白浓度,g / l; RVt是心脏右心室的舒张末期容积,cm; SPPA是肺动脉的收缩压值,毫米汞柱。如果观察到值F> 0,则可预示临床效果为阳性,而值F <0则为阴性或不存在临床效果。;效果:该方法的应用允许仅对表现出阳性临床表现的患者开IGCS应达到的效果,促进对COPD患者的医疗救助质量的改善,并减少患者不希望的类固醇负荷。2ex

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