CARBONATES OF PHENICOL ANTIBIOTICS

摘要

FIELD: chemistry.;SUBSTANCE: invention relates to carbonate derivatives of phenicols which are compounds of formula 1 , where R₁ is selected from a group comprising , R₂ is selected from a group comprising dichloromethyl, difluoromethyl, chlorofluoromethyl, chloromethyl and methyl, R₃ is selected from a group comprising hydroxymethyl, fluoromethyl, difluoromethyl, trifluoromethyl and CH₂O-C(O)O-R₅, R₄ and R₅ are independently selected from a group comprising straight or branched substituted C_1-10alkyl or C_1-10carboalkoxy or unsubstituted C_1-10alkyl, C_1-10cycloalkyl, C_1-10alkoxyalkyl, phenyl, phenylalkyl, straight or branched substituted C_1-10alkyl or unsubstituted C_1-10alkenyl or C_1-10cycloalkenyl or solvate thereof.;EFFECT: improved properties of compounds.;11 cl, 15 tbl, 35 ex, 7 dwg