Analysis system with coupling of gpc and nmr - spectroscopy, in particular for the analysis of polymer-containing measurement samples

摘要

An analysis system (1) for analysing a sample,comprising a heavy-duty gel permeation - chromatograph (14) which, by means of a nuclear magnetic resonance (= nmr) is coupled - spectrometer,the chromatography graph (14) a heavy-duty gel permeation - chromatography (= gpc) - separation column (6) with porous particles (21) is filled,is characterized by the,that - the nmr spectrometer as a low field - - nmr spectrometer (8) with a permanent magnet system (9) for generating a b₀-Field of the nmr - spectrometer is designed,the lower field - - nmr spectrometer (8) a shim - a system (10), with which, in a circular cylindrical sample volume (27) of at least 5 mm in diameter and at least 15 mm in length a homogeneity of the b₀-Field of 0,5 ppm or more, preferably 0,1 ppm or better, can be achieved, and wherein the lower field - - nmr spectrometer (8) further comprises a lock function (29) for compensating a drift of the b₀-Field comprises,and in that the chromatography graph (14) a gpc - separating columns system (6a), the at least one of the gpc - separation column (6), wherein all the gpc - separation columns (6) of the gpc - separating columns system (6a) together an internal volume of at least 45 cm³, preferably at least 100 cm³, have. The present invention makes possible a quantitative and qualitative chemical analysis of samples, the substances with different molecular size, and in the case of reduced expenditures for apparatus.