Bioreactor for the conversion of an educt to a product using an biocatalyst, which is reversibly immobilized on and/or in a controllable carrier material, comprises tubular reactor chamber, and supporting body that is part of reactor wall

摘要

The bioreactor (1) for the conversion of an educt to a product using an biocatalyst, which is reversibly immobilized on and/or in a controllable carrier material (3), comprises a tubular reactor chamber (2), and a supporting body, which is a part of a reactor wall and/or a mounting part and a filling body arranged in the bioreactor during the catalyzed reaction. The carrier material is bound on the surface of the supporting body, and forms a microscale surface layer of the supporting body, where the layer thickness of the microscale surface layer is 20 mu m or less. The bioreactor (1) for the conversion of an educt to a product using an biocatalyst, which is reversibly immobilized on and/or in a controllable carrier material (3), comprises a tubular reactor chamber (2), and a supporting body, which is a part of a reactor wall and/or a mounting part and a filling body arranged in the bioreactor during the catalyzed reaction. The carrier material is bound on the surface of the supporting body, and forms a microscale surface layer of the supporting body, where the layer thickness of the microscale surface layer is 20 mu m or less. The carrier material forms a nanoscale surface layer of the supporting body, and is chemically, physically and/or mechanically fixed. The carrier material is fixed to an inner lateral surface of the reactor wall limiting the reactor chamber. The carrier material is bound on a cell fabric, polyethylene film or polypropylene film. The release of the biocatalyst by and/or from the carrier material or the immobilization of the biocatalyst on and/or in the carrier material is controllable by a change of the environmental conditions of the carrier material. The carrier material is fixed onto the supporting body for increasing the mechanical stability on and/or in the supporting body with high mass stability of the carrier material.