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mutant herpes simplex virus and use thereof in the treatment of squamous cell carcinoma
mutant herpes simplex virus and use thereof in the treatment of squamous cell carcinoma
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机译:突变单纯疱疹病毒及其在鳞状细胞癌治疗中的应用
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摘要
An herpes simplex virus wherein the herpes simplex virus genome comprises nucleic acid encoding an antisense to the squamous cell carcinoma related oncogene (asSCCRO); and an herpes simplex virus wherein the herpes simplex virus genome comprises nucleic acid encoding a short interfering ribonucleic acid (siRNA) molecule that is capable of repressing or silencing expression of squamous cell carcinoma related oncogene (SCCRO) nucleic acid or polypeptide are disclosed together with methods for generation and applications of such viruses.
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