首页> 外国专利> METHOD FOR INSPECTING IRREGULAR PULSE BASED ON SINGLE NUCLEOTIDE POLYMORPHISM OF LONG ARM 24 REGION OF CHROMOSOME 1, NEURL GENE, OR CUX2 GENE

METHOD FOR INSPECTING IRREGULAR PULSE BASED ON SINGLE NUCLEOTIDE POLYMORPHISM OF LONG ARM 24 REGION OF CHROMOSOME 1, NEURL GENE, OR CUX2 GENE

机译:基于长臂24​​号染色体,neurl基因或cux2基因的单核苷酸多态性的不规则脉动检测方法

摘要

PROBLEM TO BE SOLVED: To provide a method for inspecting an irregular pulse of atrial fibrillation or the like.SOLUTION: The single nucleotide polymorphism existing in a long arm 24 region of a chromosome 1, a NEURL gene, or a CUX2 gene is analyzed. The single nucleotide polymorphism is a single nucleotide polymorphism in a base corresponding to a base of the base No. 61 of a specific base sequence or a base in relation of linkage disequilibrium with the base. A probe for inspecting the irregular pulse having a complementary sequence, and a primer for inspecting the irregular pulse that can amplify the region including the base of base No. 61 are provided. The risk of development and/or existence/nonexistence of the irregular pulse are inspected based on the analysis result.
机译:解决的问题:提供一种检查心律不齐的房颤等的方法。解决方案:分析存在于染色体1,NEURL基因或CUX2基因的长臂24区中的单核苷酸多态性。单核苷酸多态性是在碱基中的单核苷酸多态性,其对应于特定碱基序列的61号碱基的碱基或与该碱基的连接不平衡有关的碱基。提供用于检查具有互补序列的不规则脉冲的探针和用于检查不规则脉冲的引物,该引物可以扩增包括61号碱基的碱基在内的区域。基于分析结果,检查不规则脉冲的发生和/或不存在的风险。

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