USE OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR FOR MANUFACTURING MEDICAMENT FOR TREATMENT OF DIABETIC NEUROPATHY

摘要

PROBLEM TO BE SOLVED: To provide new use of a statin drug in the improvement of diabetic neuropathy, particularly in improving nerve conduction velocity and nerve blood flow in patients suffering diabetes.SOLUTION: Pharmaceutical combinations of the statin drug and other agents known to improve diabetic neuropathy such as an aldose reductase inhibitor (ARI), an angiotensin converting enzyme (ACE) inhibitor, and an angiotensin II (AII) antagonist are useful in the prevention and treatment of the complications of diabetes.