Optical activity production method of the cyclopropane carboxylic acid ester compound and asymmetrical copper complex null (A)1

摘要

PROBLEM TO BE SOLVED: To provide a method for profitably producing an optically active cyclopropanecarboxylic ester compound.;SOLUTION: This method for producing the optically active cyclopropanecarboxylic ester compound is characterized by reacting a prochiral olefin with a diazoacetate in the presence of an asymmetric copper complex prepared by the reaction of three components consisting of (A) a univalent or divalent copper compound, (B) an optically active bisoxazoline compound represented by formula (1) and (C) a fluorine compound represented by the formula: A-MF₆ (A is Li, Na, K, Ag or trityl; M is P, As or Sb).;COPYRIGHT: (C)2006,JPO&NCIPI