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METHOD FOR PRODUCING 4-VINYL CATECHOL POLYMERIZATION COMPOUND, OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF

机译:制备4-乙烯基儿茶酚聚合化合物或其药学上可接受的盐的方法

摘要

PROBLEM TO BE SOLVED: To provide a method for efficiently producing a 4-vinyl catechol polymerization compound, or a pharmaceutically acceptable salt thereof having excellent anticancer activity and lipase inhibitory activity, a lipase inhibitor, an anti-obesity agent, skin disease therapeutic agent and anticancer agent containing the 4-vinyl catechol polymerization compound, or the pharmaceutically acceptable salt thereof, and a food, a pharmaceutical agent or a cosmetic product containing the 4-vinyl catechol polymerization compound, or the pharmaceutically acceptable salt thereof.;SOLUTION: The method for producing a 4-vinyl catechol polymerization compound represented by the formula (1), or a pharmaceutically acceptable salt thereof comprises heating caffeic acid in the presence of a metal salt. Also provided are a lipase inhibitor, an anti-obesity agent, skin disease therapeutic agent and anticancer agent, and a food, a pharmaceutical agent or a cosmetic product containing the 4-vinyl catechol polymerization compound represented by the formula (1), or the pharmaceutically acceptable salt thereof.;COPYRIGHT: (C)2012,JPO&INPIT
机译:解决的问题:提供有效地生产具有优异的抗癌活性和脂肪酶抑制活性的4-乙烯基邻苯二酚聚合化合物或其药学上可接受的盐的方法,脂肪酶抑制剂,抗肥胖剂,皮肤病治疗剂和含有4-乙烯基邻苯二酚聚合化合物或其药学上可接受的盐的抗癌剂,以及含有4-乙烯基邻苯二酚聚合化合物或其药学上可接受的盐的食品,药物或化妆品。用于制备由式(1)表示的4-乙烯基邻苯二酚聚合化合物或其药学上可接受的盐的步骤包括在金属盐的存在下加热咖啡酸。还提供了脂肪酶抑制剂,抗肥胖剂,皮肤病治疗剂和抗癌剂,以及包含由式(1)表示的4-乙烯基邻苯二酚聚合化合物或其药学上可接受的盐。;版权:(C)2012,JPO&INPIT

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