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Anionic or cationic dendrimer antimicrobial or antiparasitic composition
Anionic or cationic dendrimer antimicrobial or antiparasitic composition
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机译:阴离子或阳离子树状大分子抗微生物或抗寄生虫组合物
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摘要
To inhibit, prophylactically or therapeutically, a bacterial, yeast, fungal, or parasitic agent in a patient, an effective amount of a dendrimer is administered to the patient, which dendrimer has a plurality of terminal groups, at least one of which has an anionic- or cationic-moiety covalently bonded or linked thereto. The anionic-containing moiety is not a disaccharide or oligosaccharide moiety, and, where the anionic-containing moiety is a neuraminic- or sialic acid-containing. moiety, it is modified in the 4-position by substitution with an amino, amido, cyano, azido or guanido group, or is unsaturated.
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