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Use of effective products extracted from ginger rhizomes in treating diseases associated with Helicobacter pylori

机译:从姜根茎中提取的有效产品在治疗幽门螺杆菌相关疾病中的用途

摘要

Potent extracts from rhizomes of Zingiber officinale may be used to treat a disease associated with Helicobacter pylori such as gastritis, gastric ulcer or duodenal ulcer. The potent product is prepared by a process including the steps of (a) preparing a crude extract from rhizomes of Zingiber officinale, said crude extract comprising 6-ginerol and 6-shogaol, (b) introducing the crude extract to a reverse phase chromatography column and eluting with a first eluent having a polarity that is lower that water to obtain a first potent fraction and then extracting with a second eluent that is lower in polarity than the first eluent, to obtain a second potent fraction. The second potent fraction is substantially free of both 6-ginerol and 6-shogaol. Elution may also be carried out on a normal phase chromatography column.
机译:来自姜的根茎的有效提取物可用于治疗与幽门螺杆菌相关的疾病,例如胃炎,胃溃疡或十二指肠溃疡。该有效产物通过包括以下步骤的方法制备:(a)从姜的根茎中制备粗提物,所述粗提物包含6-甘油和6-松果酚,(b)将粗提物引入反相色谱柱中。然后用极性比水低的第一洗脱液洗脱得到第一有效级分,然后用极性比第一洗脱剂低极性的第二洗脱液进行萃取,得到第二有效级分。第二有效级分基本上不含6-甘油和6-shogaol。洗脱也可以在正相色谱柱上进行。

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