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Paclitaxel / liposome composition for cancer treatment and method for producing the same

机译:用于癌症治疗的紫杉醇/脂质体组合物及其制备方法

摘要

The present invention relates to a paclitaxel-based liposome composition for treatment of cancer, which consists substantially of the following materials by weight: paclitaxel 2-5 parts, phosphatide 20-200 parts, cholesterol 2-30 parts, amino acids 0.3-4 parts, and lyophilized excipient 10-75 parts. The products according to the present invention do not contain polyoxyethylated castor oil, and substituted the toxic and expensive adjuvant with nontoxic media and easily obtained adjuvant, and can be actualized e in industry. They have the advantages of low toxicity, good tolerance for patient, good water solubility and better stability.
机译:本发明涉及用于治疗癌症的基于紫杉醇的脂质体组合物,其基本上由以下重量份组成:紫杉醇2-5份,磷脂20-200份,胆固醇2-30份,氨基酸0.3-4份和冻干的赋形剂10-75份。本发明产品不含聚氧乙烯蓖麻油,用无毒介质代替有毒,昂贵的佐剂,易获得佐剂,可在工业上实现。它们具有毒性低,对患者的耐受性好,水溶性好和稳定性更好的优点。

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