Labeling reagent, labeled analyte, and fragment ions derived therefrom, including a mixture of labeling reagent and labeled analyte, and methods for their analysis

摘要

The present invention relates to fragment ions derived therefrom, and including mixtures thereof analyte labeling reagents, labeled. The present invention (including the labeled reagent of N- substituted piperazine acetic acid-based), a method of generating the fragment ions derived therefrom, as well as the labeled analyte and its (including mixtures thereof) labeled analyte labeling reagent about the methods of analysis. According to the method of the present invention, the analyte to be quantified is labeled. Itself analyte labeled analyte, a fragment of the labeled fragments and at least one of the analyte and / or can be quantified by mass spectrometry.