Methods of Automated Spectral and Chromatographic Peak Detection and Quantification without User Input

摘要

Methods are disclosed for automatically analyzing a chromatography/mass spectrometry spectrum characterized by at least a time-related variable, a mass-related variable and an ion-abundance-related variable, comprising the steps of: receiving a portion of the spectrum from a chromatography/mass spectrometry apparatus while the chromatography/mass spectrometry apparatus is concurrently generating another portion of the spectrum; automatically subtracting a baseline from the portion of the spectrum so as to generate a baseline-corrected spectrum portion; automatically determining if at least one spectral peak occurs in the baseline-corrected spectrum portion; and reporting information relating at least to the number of peaks automatically determined in the portion of the chromatography/mass spectrometry spectrum.