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Novel compounds which have a protective activity with respect to the action of toxins and of viruses with an intracellular mode of action

机译:对毒素和病毒具有细胞内作用方式具有保护作用的新型化合物

摘要

The subject matter of the present invention is novel families of compounds which are aromatic amine, imine, aminoadamantane and benzodiazepine derivatives, medicaments comprising same and the use thereof as inhibitors of the toxic effects of toxins with intracellular activity, such as, for example, ricin, and of viruses that use the internalization pathway for infecting cells.
机译:本发明的主题是新颖的化合物族,它们是芳族胺,亚胺,氨基金刚烷和苯并二氮杂derivatives衍生物,包含其的药物及其作为具有细胞内活性的毒素的毒性作用的抑制剂的用途,例如蓖麻毒素,以及使用内部化途径感染细胞的病毒。

著录项

  • 公开/公告号US2012283249A1

    专利类型

  • 公开/公告日2012-11-08

    原文格式PDF

  • 申请/专利号US20090999576

  • 申请日2009-06-17

  • 分类号A61K31/137;C07C211/29;C07C215/50;C07C217/58;C07C229/38;A61K31/24;C07D213/38;A61K31/4402;A61K31/4406;A61K31/4409;C07D307/52;A61K31/341;C07D333/20;A61K31/381;C07D233/64;A61K31/417;C07D215/12;A61K31/47;C07D451/02;A61K31/46;C07D243/24;A61K31/5513;C07D243/12;A61K31/551;C07D487/04;A61K31/138;A61K31/166;A61K31/18;A61P39/02;A61P31/12;C07C211/27;

  • 国家 US

  • 入库时间 2022-08-21 17:32:28

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