METHOD FOR ESTIMATING THE PHYSIOLOGICAL PARAMETERS DEFINING THE EDEMA INDUCED UPON INFUSION OF FLUID FROM AN INTRAPARENCHYMALLY PLACED CATHETER

摘要

A method for estimating the physiological parameters defining the edema induced upon infusion of fluid from an intraparenchymally placed catheter including; acquisition of patient-specific medical data; estimation of pertinent tissue microstructure based on the patient-specific medical data and/or generalized information derived or drawn from one or more of the following: experience, literature, modeling, studies, research, analysis; acquisition of information about delivery parameters, and/or delivery device geometry, and/or fluid properties, such as: delivery device trajectory, flow rate, pressure, catheter diameter, catheter profile, fluid viscosity, fluid molecular size; and computing a field of values of predicted extracellular volume fraction over the tissue region using the information obtained above. According to a further aspect, a method of infusing or planning and/or monitoring an infusion of a contrast agent such that the distribution of such agent can be detected by medical data acquisition and observing and/or measuring the backflow length along the catheter track.