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POST-ACUTE ELECTRICAL STIMULATION TREATMENT OF ADVERSE CEREBROVASCULAR EVENTS

机译:急性脑血管事件的急性后电刺激治疗

摘要

A method for treatment is provided, including identifying that a subject has suffered from an adverse cerebrovascular event, excluding Alzheimer's disease and Parkinson's disease. Responsively to the identifying, beginning at least nine hours after the event, electrical stimulation is applied to a site of the subject selected from the group consisting of: a sphenopalatine ganglion (SPG), a greater palatine nerve, a lesser palatine nerve, a sphenopalatine nerve, a communicating branch between a maxillary nerve and an SPG, an otic ganglion, an afferent fiber going into the otic ganglion, an efferent fiber going out of the otic ganglion, an infraorbital nerve, a vidian nerve, a greater superficial petrosal nerve, and a lesser deep petrosal nerve. The stimulation is configured to excite nervous tissue of the site at a strength sufficient to induce at least one neuroprotective occurrence selected from the group consisting of: an increase in cerebral blood flow (CBF) of the subject, and a release of one or more neuroprotective substances.
机译:提供一种治疗方法,包括鉴定受试者患有不良的脑血管事件,但不包括阿尔茨海默氏病和帕金森氏病。响应于在事件发生后至少九小时开始识别,对受试者的部位施加电刺激,该部位选自:蝶phen神经节(SPG),greater大神经,a小神经,蝶ala神经,上颌神经与SPG之间的连通分支,耳神经节,进入耳神经节的传入纤维,耳蜗神经外的传出纤维,眶下神经,vi神经,更大的浅表睑神经,以及较小的深部神经。刺激被配置为以足以引起选自以下的至少一种神经保护性发生的强度来激发该部位的神经组织:受试者的脑血流量(CBF)的增加,以及一种或多种神经保护性的释放。物质。

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