SOLID-STATE METHOD FOR PRODUCING FUNCTIONALIZED CALCIUM PHOSPHATE HYBRID ORGANIC/INORGANIC CHEMICAL SYSTEMS FOR DENTAL REMINERALIZATION APPLICATIONS

摘要

A method of repairing weakened teeth, including combining a first predetermined amount of an inorganic calcium source with a second predetermined amount of an organic material to define a mixture, placing the mixture in a milling vessel operationally connected to a planetary mill, introducing milling media into the milling vessel, milling the mixture to impart sufficient kinetic energy to break down the organic and inorganic materials into substantially smaller intermediate particles and fuse the intermediate particles together to yield functionalized molecules having both organic and inorganic chemical characteristics, combining a functionalized calcium phosphate/organic compound with a fluoridated formulation to define a hybrid system, and applying the hybrid system to the weakened teeth.