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Methods for modulating de novo hepatic lipogenesis by modulating XBP-1 activity
Methods for modulating de novo hepatic lipogenesis by modulating XBP-1 activity
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机译:通过调节XBP-1活性调节新生肝脏脂肪生成的方法
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摘要
The invention provides methods and compositions for modulating the expression, processing, post-translational modification, stability and/or activity of XBP-1 protein, or a protein in a signal transduction pathway involving XBP-1 to treat dyslipidemias and steatosis disorders. The present invention also pertains to methods for identifying compounds that modulate the expression, processing, post-translational modification, and/or activity of XBP-1 protein or a molecule in a signal transduction pathway involving XBP-1.
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