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Tamibarotene capsule preparation

机译:他米巴罗汀胶囊制剂

摘要

The present invention provides a practical preparation form of Tamibarotene and dosage form thereof, which exhibit high absorptivity by the body with minimized toxicity, and which are safe and stable without any risk of contamination. It is provided a Tamibarotene capsule preparation which encapsulates a composition comprising an oil component as its base and Tamibarotene as an active ingredient dissolved in the base. It is preferred that the oil component be propylene glycol fatty acid esters or polyethylene glycols. It is also preferred that the Tamibarotene capsule preparation comprise 0.1-50 mg/mL of the Tamibarotene based on the oil component.
机译:本发明提供了塔米巴罗汀的实用制剂形式及其剂型,其在体内具有高吸收性,且毒性最小,并且是安全稳定的,没有任何污染的危险。提供了一种坦米巴罗汀胶囊制剂,该制剂包封包含油成分作为其基质和坦米巴罗汀作为溶解于该基质中的活性成分的组合物。油成分优选为丙二醇脂肪酸酯或聚乙二醇。还优选的是,他米巴罗汀胶囊制剂包含基于油成分的0.1-50mg / mL的他米巴罗汀。

著录项

  • 公开/公告号US8252837B2

    专利类型

  • 公开/公告日2012-08-28

    原文格式PDF

  • 申请/专利权人 HISAO EKIMOTO;

    申请/专利号US20080593866

  • 发明设计人 HISAO EKIMOTO;

    申请日2008-03-28

  • 分类号A61K31/195;A61K9/48;

  • 国家 US

  • 入库时间 2022-08-21 17:28:53

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