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Antibacterial agent and therapeutic agent for johne's disease containing the same
Antibacterial agent and therapeutic agent for johne's disease containing the same
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机译:抗菌剂和含约翰逊氏病的治疗剂
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摘要
An antibacterial agent having high antibacterial activity against Mycobacterium avium subsp. paratuberculosis is provided. Specifically, the antibacterial agent of the present invention having high antibacterial activity against Mycobacterium avium subsp. paratuberculosis is a caprazamycin derivative represented, for example, by the following general formula (II):; wherein Me is a methyl group; and R1 is a straight or substantially straight chain alkyl group having 5 to 21 carbon atoms, a straight or substantially straight chain alkenyl group having 5 to 21 carbon atoms, a cycloalkyl group having 5 to 12 carbon atoms, or a phenyl group substituted at the para-position with a straight chain alkyl group having 1 to 14 carbon atoms, a straight chain alkoxy group having 1 to 9 carbon atoms or a cycloalkyl group having 5 to 12 carbon atoms.
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机译:对禽分枝杆菌 I>亚种具有高抗菌活性的抗菌剂。提供了肺结核 I>。具体地说,本发明的抗菌剂对鸟分枝杆菌具有较高的抗菌活性。 副结核 I>是一种卡扎霉素衍生物,其例如由以下通式(II)表示: 化学>其中Me是甲基; R 1是碳原子数为5〜21的直链或大致直链的烷基,碳原子数为5〜21的直链或大致直链的链烯基,碳原子数为5至12的环烷基。或在对位被碳数为1至14的直链烷基,碳数为1至9的直链烷氧基或碳数为5至12的环烷基取代的苯基。
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