Derivatives of 8-epiblechnic acid and their effects on down-regulation of endothelin (ETA) receptor mRNA

摘要

The present application discloses derivatives of 8-epiblechnic acid and use thereof in treating a disease related to endothelin receptor A or endothelin-1 (ET-1) over-expression, such as hypertension, cancer, atherosclerosis, and myocardial infarction.