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Method to assess the severity of rheumatoid arthritis by measuring anti-CCP and serum amyloid A
Method to assess the severity of rheumatoid arthritis by measuring anti-CCP and serum amyloid A
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机译:通过测量抗CCP和血清淀粉样蛋白A评估类风湿关节炎严重程度的方法
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摘要
Disclosed is a method for assessing a severity of rheumatoid arthritis. The method involves measuring in a patient sample a concentration of anti-cyclic citrullinated peptides (anti-CCP) and serum amyloid A, combining the concentrations determined to obtain a combined value, and comparing the combined value to a cut-off value established from a reference population. In another method, a marker selected from the group consisting of C-reactive protein (CRP), interleukin 6 (IL-6), S100 protein, osteopontin, rheumatoid factor (RF), matrix metalloprotease 1 (MMP-1), matrix metalloprotease 3 (MMP-3), hyaluronic acid, and soluble CD14 (sCD14) may also be determined along with the anti-CCP and serum amyloid A.
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