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Linoleic acid preparations for the topical treatment of male and female pattern androgenetic alopecia, age-related alopecia, and keratosis pilaris

机译:亚油酸制剂,用于局部治疗男性和女性型雄激素性脱发,年龄相关性脱发和毛发角化病

摘要

A preparation for the topical application of linoleic acid to treat male and female androgenetic alopecia, age-related alopecia, and keratosis pilaris contains between about 0.1% and about 10%, preferably between about 1% and about 5%, and specifically about 2% linoleic acid by volume in its carrier vehicle. This acts to correct the local linoleic acid deficiency that exists in the follicles in these conditions and provides linoleic acid to suppress growth of Propionibacterium acnes with resultant reduction in its porphyrin production which in turn reduces microinflammation and altered keratinization that damages follicles and eliminates functioning follicles in alopecia and causes follicle plugging in keratosis pilaris.
机译:用于局部施用亚油酸以治疗男性和女性雄激素性脱发,年龄相关性脱发和毛发角化病的制剂包含约0.1%至约10%,优选约1%至约5%,特别是约2%。亚油酸在其载体中的含量。这可以纠正在这种情况下卵泡中存在的局部亚油酸缺乏症,并提供亚油酸来抑制痤疮丙酸杆菌的生长,从而减少其卟啉生成,从而减少微炎症和改变角质化,从而损害毛囊并消除脱发的功能性毛囊,并导致毛发角化病中的毛囊堵塞。

著录项

  • 公开/公告号US8067470B2

    专利类型

  • 公开/公告日2011-11-29

    原文格式PDF

  • 申请/专利权人 WILLIAM ROBERT MCDANIEL;

    申请/专利号US20080012198

  • 发明设计人 WILLIAM ROBERT MCDANIEL;

    申请日2008-02-01

  • 分类号A61K31/201;

  • 国家 US

  • 入库时间 2022-08-21 17:25:57

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