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Method of increasing muscle mass by administering a myostatin binding agent
Method of increasing muscle mass by administering a myostatin binding agent
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机译:通过施用肌肉生长抑制素结合剂增加肌肉质量的方法
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摘要
The present invention provides binding agents comprising peptides capable of binding myostatin and inhibiting its activity. In one embodiment the binding agent comprises at least one myostatin-binding peptide attached directly or indirectly to at least one vehicle such as a polymer or an Fc domain. The binding agents of the present invention produced increased lean muscle mass when administered to animals and decreased fat to muscle ratios. Therapeutic compositions containing the binding agents of the present invention are useful for treating muscle-wasting disorders and metabolic disorders including diabetes and obesity.
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