Albumin polypeptide FUSIONS and butyrylcholinesterase (BChE) for the treatment of cocaine abuse

摘要

Method for reducing the Biological effects of exposure to cocaine in a primate.The Method comprises administering an amount of a primate to Albumin fusion protein (polypeptide of butyrylcholinesterase, BChE) comprising amino acid substitutions a227s, s351g, a356w and y360g, where the amount of the fusion protein is effective to cause the atenu Action of Biological effect of exposure to cocaine in the primate.