Piperazin - purine Compound Pharmaceutical composition that comprises and its use for preparing Medicine useful for the Treatment or prevention of Pain

摘要

Piperazin - purine Compound of the formula (1) wherein R1 is IC or CH3; R2 is Oh, OCH3, h CH2OH or ch2och3; R3 or R4 is combined with to form a pyrrolidin-2-one merged c1-3 alkyl; R4 is fluoroalquilo C1, C 2, (OR) or CH3R co2ch3 is H or CH3; R5, R6 is ch2och3; h, CH3 or combined with R5 for Sea a cyclopropane Ring; and N is 0 OR 1; or a pharmaceutically acceptable Salt thereof.Pharmaceutical composition containing same and use for preparing Medicine useful for the Treatment or prevention of pain.