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SYSTEM FOR PHOTODYNAMIC THERAPY IN ONCOLOGICAL DISEASES

机译:肿瘤疾病的光动力治疗系统

摘要

The system for photodynamic therapy in oncological diseases, malignant dermatologic diseases in particular, is applicable in medicine. It comprises two independent laser sources with different wavelength (1 and 2) combined with light guides (3), a heat source (4), and a heat sensor (5). During therapy, photosensibilizer solution is preliminarily introduced into the patientÆs organism, which gets concentrated in the malignant formation. This is followed by heating the formation and the area around it with a heat source up to a temperature of 42-43 degrees, which is kept permanent, and simultaneous irradiation by the two laser sources during therapy. The wavelength of one of the laser radiations ensures the maximum absorption by the photosensibilizer leading to the photochemical reaction with the formation of the syngletic oxygen. The second wavelength used in combination with the heat action stimulates further the creation of the molecular oxygen in the area. The quantum yield of the therapy process is raised up to approximately 18 percents.
机译:用于肿瘤疾病特别是恶性皮肤病的光动力治疗的系统可用于医学。它包括两个独立的具有不同波长的激光源(1、2)和光导(3),一个热源(4)和一个热传感器(5)。在治疗期间,将光敏剂溶液预先引入患者的生物体中,该生物体集中在恶性组织中。随后,用热源将地层及其周围区域加热至42-43度,该温度保持永久不变,并在治疗过程中同时使用两个激光源进行照射。激光辐射之一的波长确保了光敏剂的最大吸收,从而导致光化学反应并形成合成氧。与热作用结合使用的第二波长进一步刺激了该区域中分子氧的产生。治疗过程的量子产率提高到大约18%。

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