compound, use of a compound, radiopharmaceutical formulation, method for in vivo diagnosis or imaging of nmda-mediated disease in a patient, process for preparing a compound, and kit for preparing a radiopharmaceutical formulation

摘要

COMPOUND, USE OF A COMPOUND, RADIOPHARMACEUTICAL FORMULATION, METHOD FOR DIAGNOSTIC OR IMAGE FORMATION OF NMDA-MEDIATED DISEASE IN A PATIENT, PROCESS FOR PREPARATION OF A COMPOUND, KIT FOR PREPARATION OF PREPARATION. The invention provides a compound of formula (I); or a salt or solvate thereof, wherein: R4 is hydrogen or C1-4 alkyl; R 2 and R 4 are all independently selected from C 1-4 alkyl, C 1-4 alkyl and C 1-4 fluoroalkyl. provided that at least one of R 2 and R 4 is [1-1C] alkyl or C 1-4 fluoroalkyl; and R3 is halo. Such compounds having use for imaging central nervous system receptors.