Acetamide derivatives, replaced by N-hetero or 2-hetero compounds, act as modulators of signal wave groups; synthesize drugs containing these components; and their use in cancer treatment, rejecting Rio n transplantation, osteitis, Parkinson's and so on.

摘要

Compounds derived from Acetamidas replaced by N - (hetero) and 2 - aryl - aryl - (hetero),Pharmaceutical modulators of Wnt; composition; method to inhibit WNT signaling; and its use for the treatment of keloids, fibrosis, proteinuria, kidney graft rejection, Osteoarthritis,Retinopathy, among others.