LRK2 is inhibited by substituted pyrazolpyridan derivatives, its preparation procedure, pharmacological synthesis, pharmacological combination, and the use of the compound to prevent or treat selected cancer and neurodegenerative diseases.

摘要

Compound derived from pirazolopiridina replacedLRRK2 kinase inhibitor; procedure of preparation of said Compound Pharmaceutical composition, pharmaceutical use of compound; Combination; to prevent or treat a disorder selected dAnd Cancer and Neurodegenerative Diseases.