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Low dose precision formulation of pirimid and short-term dose regulation of active keratinase

机译:派瑞米定的低剂量精密配方和活性角蛋白酶的短期剂量调节

摘要

Are revealed and described Pharmaceutical formulations and Methods for providing topical or transdermal 1 - isobutyl - 1H imidazo [4,5-c] quinolin-1 - 4 - Amine (aka, also known as 1 - (2-methylpropyl) - 1H imidazo [4,5-c] quinolin-1 - 4 - amino, aka imiquimodTherapies to treat Actinic keratosis with Shorter duration to the currently prescribed for Aldara 5% imiquimod Cream Commercially available, as currently approved by the food and Drug Administration of the United States of America (FDA).More specifically, Imiquimod formulations are revealed and described in less Concentrated Dose to provide an effective Dose to treat Actinic keratosis with an acceptable Safety Profile.But with a dosing regimen that is shorter and more suitable for use by patients the dose regimen currently approved by the FDA for Aldara 5% imiquimod Cream.
机译:揭示和描述了提供局部或透皮1-异丁基-1H咪唑并[4,5-c]喹啉1-4-胺(又名1-(2-甲基丙基)-1H咪唑并[ 4,5-c]喹啉1-4-氨基,又称咪喹莫特,用于治疗光化性角化病的疗法,持续时间短于目前Aldara 5%咪喹莫特乳膏的处方药,市售,目前已获美国食品和药物管理局批准美国(FDA)更详细地披露和描述了咪喹莫特的配方,该配方的浓度较低,可提供有效的剂量来治疗光化性角化病,并具有可接受的安全性,但给药方案较短,更适合患者使用FDA目前批准的Aldara 5%咪喹莫特乳霜用药方案。

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