首页> 外国专利> Derivatives of 6 - (6-o - cicloalquil or - NH - 6 - - cicloalquil triazolopiridazina sulfanyl) benzotiazoles and benzimidazoles: preparation, application as Medicines and use as inhibitors of the Met

Derivatives of 6 - (6-o - cicloalquil or - NH - 6 - - cicloalquil triazolopiridazina sulfanyl) benzotiazoles and benzimidazoles: preparation, application as Medicines and use as inhibitors of the Met

机译:6-(6-o-环氯喹或-NH-6--环氯吡唑并三叠氮杂亚砜)苯并噻唑和苯并咪唑的衍生物:制备,药物用途和作为Met抑制剂的用途

摘要

Invention refers to a new formula product (1), wherein: RA stands for simple or double bond; RA stands for s-o-cycloquilo o-n h-cycloquilo; x stands for s, so or SO2; a stands for NH or s; W stands for H, tar or cor stands for r-cycloquilo; tar; alcox; o-fenilo; O - (CH2) n-fenilo con n = 1-4; R1 for H, or AIQ, R2 for H, cycloquilo, heterosexual or aspha or R1 and R2 for N, or optionally containing o, s, N and / or NH; all these optional radicals are replaced; these products exist in the form of various isomers and salts, Mainly as an MIT inhibitor
机译:发明涉及一种新配方产品(1),其中:RA代表单键或双键; RA代表s-o-环quilo o-n h-环quilolo; x代表s,所以代表SO2; a代表NH或s; W代表H,tar或cor代表r-cycloquilo;柏油;酒精o-fenilo; O-(CH 2)n-苯胺基con n = 1-4; R1代表H,或AIQ,R2代表H,环喹啉,异性或沥青;或R 1和R 2为N,或任选地含有o,s,N和/或NH;所有这些可选的部首被替换;这些产品以各种异构体和盐的形式存在,主要是作为MIT抑制剂

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