u0431u0438u043eu0441u0438u043du0442u0435u0442u0438u0447u0435u0441u043au0438u0439 u043fu0438u0440u0440u043eu043bu0438u043du043au0430u0440u0431u043eu043au0441u0438u043bu0438u0437u0438u043d and site specific modification of the protein by chemical modification of u043fu0438u0440u0440u043eu043bu0438u043du043au0430u0440u0431u043eu043au0441u0438u043bu0438u0437u0438u043du0430 and u043fu0438u0440u0440u043eu043bu0438u0437u0438u043du0430

摘要

in the application described u043fu0438u0440u0440u043eu043bu0438u043du043au0430u0440u0431u043eu043au0441u0438u043bu0438u0437u0438u043d (pcl), equivalent to the u043fu0438u0440u043eu043bu0438u0437u0438u043du0430, which represents the natural received u0431u0438u043eu0441u0438u043du0442u0435u0442u0438u0447u0435u0441u043au0438u043c way amino acids, and methods biosynthesis pcl.the application also describes u043fu043eu043bu0438u043fu0435u043fu0442u0438u0434u044b proteins, and peptides, which contain built-in pcl, pcl and ways of embedding in the u043fu043eu043bu0438u043fu0435u043fu0442u0438u0434u044b, proteins, and peptides.the application also describes the site specific modification of proteins, polypeptides and peptides containing a built-in pcl or pyrrolysine.the application also describes the sewing of proteins, polypeptides and peptides containing a built-in pcl or pyrrolysine.