OPTIMIZED EARLY / LATE PROMOTOR IN COMBINATION WITH REPEATED VACCINATION ASSISTED TO RESPONSE TO CYTOTOXIC T-CELLS AGAINST ANTIGENS OF RECOMBINANT VACCINES BASED ON VIRUS DEFICIENCY DEFICIENCY RESPECTIVE TO RECOMBINANT VACCINES.

摘要

The invention relates to a replication-deficient recombinant virus encoding at least one antigen and / or one antigen epitope, wherein expression of said antigen and / or antigen epitope is controlled by a transcriptional element containing at least two elements that trigger early expression of said antigen and / or an antigen epitope, and the use of said replication-deficient recombinant virus as a medicine or vaccine.