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USE OF AN LHRH ANTAGONIST FOR THE MANUFACTURE OF A MEDICAMENT FOR THE THERAPEUTIC MANAGEMENT OF EXTRAUTERINE PROLIFERATION OF ENDOMETRIAL TISSUE, CHRONIC PELVIC PAIN AND FALLOPIAN TUBE OBSTRUCTION
USE OF AN LHRH ANTAGONIST FOR THE MANUFACTURE OF A MEDICAMENT FOR THE THERAPEUTIC MANAGEMENT OF EXTRAUTERINE PROLIFERATION OF ENDOMETRIAL TISSUE, CHRONIC PELVIC PAIN AND FALLOPIAN TUBE OBSTRUCTION
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机译:LHRH拮抗剂在制造用于子宫内膜增生,慢性盆腔痛和食管阻塞的子宫内膜增生的药物治疗中的用途
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摘要
The present invention provides a method for therapeutic management of extrauterine proliferation of endometrial tissue, chronic pelvic pain and fallopian tube obstruction by short term induction treatment with an LH-RH antagonist for 4 to 12 weeks. According to another aspect of the present invention, the short term LH-RH treatment is followed by the combined or separate administration of one or more active agents selected from the group consisting of a contraceptive, preferably an oral contraceptive, a non-steroidal anti-rheumatic agent, an analgetic, an androgen other than a 17-alpha-alkyl substituted testosterone or any combinations thereof. According to a further aspect of the present invention a pharmaceutical composition comprising an LHRH antagonist and one or more active agents selected from the group consisting of a contraceptive, preferably an oral contraceptive, a non-steroidal anti-rheumatic agent, an analgetic, an androgen other than a 17-alpha-alkyl substituted testosterone or any combinations thereof are provided.
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