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NON-SEDATIVE BARBITURATE WHICH PROVIDES A NEUROPROTECTIVE EFFECT FOR PROTECTION FROM A NEUROLOGICAL DAMAGE
NON-SEDATIVE BARBITURATE WHICH PROVIDES A NEUROPROTECTIVE EFFECT FOR PROTECTION FROM A NEUROLOGICAL DAMAGE
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机译:提供防止神经损害的神经保护作用的非保守性限制
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摘要
The present invention relates to novel non-sedating barbituric acid derivatives, pharmaceutical compositions containing them and methods of neuroprotection in cases of cerebral ischemia, head trauma and other acute neurologic injuries, and prevention of resulting neuronal damage. The invention also relates to the use of non-sedating barbituric acid derivatives given in a manner and dosage effective to produce blood levels and brain levels of these drugs and/or their active metabolites sufficient to provide a therapeutic effect.
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