A COMBINATION VACCINE FOR IMMUNIZING DOGS AGAINST CANINE PATHOGENS

摘要

The present invention relates to a vaccine for immunizing dogs against canine pathogens characterized in that said vaccine consists of: a) a Leptospira cell preparation of Leptospira canicola, Leptospira grippotyphosa, Leptospira icterohaemorrhagiae, and Leptospira Pomona; wherein the amount of each Leptospira strain in the vaccine is in the range of about 100-3500 nephelometric units; b) an attenuated strain of canine distemper (CD) virus, c) an attenuated strain of canine adenovirus type 2 (CAV-2), d) an attenuated strain of canine parainfluenza (CPI) virus, e) an attenuated strain of canine parvovirus (CPV), and f) a carrier. wherein the amount of said attenuated strain of CD virus, said attenuated strain of CAV-2, said attenuated strain of CPI virus, and said attenuated strain of CPV, in said vaccine, are each in the range of l02 to l09 TCID50.