SYSTEM AND METHOD FOR OBTAINING BIOMARKERS FOR A CLINICAL DIAGNOSIS THROUGH THE DIGITAL ANALYSIS OF MEDICAL IMAGES.

摘要

Method for finding biomarkers through medical images. The method for finding biomarkers uses different image processing and variable selection algorithms for determining the set of measurements extracted from an image which act as biomarkers resulting from a bank of images and the associated clinical information thereof. The operation of the biomarker rediscovery method is based on the principle of the modern radiological equipments which have a sensitivity to changes in tissues to be analysed higher than those observed by the human eyes in the obtained images. Consequently, the method is designed for quantifying different characteristics which are not observed by the human eyes, as well as other characteristics which are visible but difficult to perceive even by trained people. The resulting biomarker may help for: (1) identifying the presence or absence of a disease, (2) quantifying the severity or progress of a disease, (3) diagnosing a disease, (4) offering a recovery prognostic, (5) quantitatively evaluating the response of a disease to a treatment, (6) determining the probability of survival, amongst others, based on a diagnosis medical image with predetermined characteristics.