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A COMPOSITION FOR USE IN RAISING AN IMMUNE RESPONSE TO P. GINGIVALIS
A COMPOSITION FOR USE IN RAISING AN IMMUNE RESPONSE TO P. GINGIVALIS
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机译:用于引起对牙龈卟啉单胞菌的免疫应答的组合物
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摘要
Disclosed is a composition for use in raising an immune response to P. gingivalis in a subject, the composition comprising an amount effective to raise an immune response of at least one antigenic or immunogenic portion of a polypeptide corresponding to accession number AAQ66654.1 (SEQ ID NO: 1), wherein the portion comprises at least 10 contiguous amino acid residues substantially identical to 10 contiguous amino acid residues of said polypeptide. Also disclosed is the use of at least one antigenic or immunogenic portion of a polypeptide in the preparation of a medicament for preventing, inhibiting or treating periodontal disease in a subject, wherein the polypeptide corresponds to accession number AAQ66654.1 (SEQ ID NO: 1).
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机译:公开了一种用于在受试者中增强对牙龈卟啉单胞菌的免疫应答的组合物,该组合物包含有效地增强对应于登录号AAQ66654.1(SEQ ID NO:1),其中该部分包含与所述多肽的10个连续氨基酸残基基本相同的至少10个连续氨基酸残基。还公开了多肽的至少一个抗原或免疫原性部分在制备用于预防,抑制或治疗受试者的牙周疾病的药物中的用途,其中所述多肽对应于登录号AAQ66654.1(SEQ ID NO:1 )。
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