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Benzothiazinone derivatives, their synthesis and their use for treatment of mammalian infections

机译:苯并噻嗪酮衍生物,其合成及其在治疗哺乳动物感染中的用途

摘要

The disclosure relates to antimicrobial compounds of formula (I), wherein the variables are as defined in the specification, their synthesis and their use as antibacterial agents in infectious diseases of mammals (humans and animals) caused by bacteria, especially diseases like tuberculosis (TB) and leprosy caused by mycobacteria. These compounds have an activity against mycobacteria as potential new tuberculosis drugs to overcome problems concerning resistance and drug intolerance.
机译:本公开涉及式(I)的抗微生物化合物,其中变量如说明书中所定义,其合成以及它们在由细菌引起的哺乳动物(人和动物)的感染性疾病,特别是诸如结核病(TB)之类的传染病中的用途。 )和由分枝杆菌引起的麻风病。这些化合物具有抗分枝杆菌的活性,可以作为潜在的新型结核药物来克服与耐药性和药物耐受性有关的问题。

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