A COMPOSITION COMPRISING LERCANIDIPINE AND AN AMOUNT OF A COLLOIDAL SILICON DIOXIDE FROM 5 TO 25 BY WEIGHT TO ENHANCE BIOAVAILABILTY AND/OR SOLUBILITY

摘要

Disclosed is a pharmaceutical composition adapted for oral administration comprising Lercanidipine or a pharmaceutically acceptable salt, or polymorph thereof, as an active ingredient, and an amount of a colloidal silicon dioxide 5 from 5% to 25 % by weight to enhance bioavailability and/or improve solubility, wherein the composition further comprises a binder which is present in an amount of from 5% to 20% by weight and a disintegrant which is present in an amount of from 5% to 15% by weight.