PROCESS FOR THE MANUFACTURE OF AN INDOLINONE DERIVATIVE IN PARTICULAR 3-Z-1-(4-(N-((4-METHYL-PIPERAZIN-1-YL)-METHYLCARBONYL)-N-METHYL-AMINO)-ANILINO)-1-PHENYL-METHYLENE-6-METHOXYCARBONYL-2-INDOLINONE

摘要

Disclosed herein is a process for the manufacture of an indolinone compound, namely 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone and its monethanesulfonate salt.