BIOREACTOR FOR THE CULTIVATION OF MAMMALIAN CELLS WHICH HAS VOLUME OF AT LEAST 4000L AND AT LEAST ONE TOP IMPELLER AND AT LEAST ONE BOTTOM IMPELLER

摘要

Disclosed is a bioreactor and bioreactor system for the cultivation of mammalian cells. The bioreactor system consists of multiple sequential cultivation bioreactors containing hydrofoil impellers in which the cells are stepped through a series of growth cycles to produce a desired cell culture.