Long term release of acetamide / tramadol in the form of oral dose

摘要

It refers to a kind of drug composition including (a) a layer of long-term release (nucleon), including such hydrolysates as powdery cellulose and starch glycerin sodium; 2. Acetaminohenon and tramadol compounds, which are divided into 5:1 to 10:1 and (b) immediate release compounds, including dometil hydrolytic delay agent selected from agr, agrosa and Goma; acetaminohenon and trabado compounds, most of which are uncomplicated; There, the complex material of tramadol is a complex HCl of karaganaranda and tramadol. The composition is also included in the long-term release layer,Hydroxypropylmethylcellulose and filling, so that the long layer can be easily dissolved in a more uniform way when dissolved. This is a long-term effective release dose in the treatment of chronic pain