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Improved reconstituted Surfactant composition containing analogues of the Surfactant Protein B (sp-b) and Surfactant protein C (sp-c)

机译:包含表面活性剂蛋白B(sp-b)和表面活性剂蛋白C(sp-c)类似物的改良的重构表面活性剂组合物

摘要

Refers to a Surfactant composition containing: a) between 1.2 and 1.8% by weight of a polypeptide similar to the Surfactant Protein sp-c Native comprising the sequence SEQ ID no. 1; (b) between 0.1 and 0.5% by weight of a polypeptide similar to the Surfactant Protein sp-b including Native Sequence SEQ ID no. 2; and (c) 12 - Dipalmitoyl SN glycero Phosphocholine (DPPC) - 3 - 1 - 2 - and Palmitoyl oleyl - sn glycero - 3 - fosfoglicerol (POPG) at a Weight ratio of between 45 and 55: 55: 45. Said composition is useful in the treatment of respiratory distress syndrome (RDS) in premature babies, Meconium Aspiration Syndrome (mas)
机译:指的是一种表面活性剂组合物,其包含:a)重量介于1.2至1.8%之间的类似于表面活性剂蛋白sp-c天然的多肽,其包含序列SEQ ID no。 1; (b)0.1至0.5%重量的类似于表面活性剂蛋白sp-b的多肽,包括天然序列SEQ ID No. 2; (c)以重量比为45至55:55:45的12-双棕榈酰基SN甘油磷酸胆碱(DPPC)3-1-2-和棕榈酰基油基-sn甘油-3-磷草烟醇(POPG)。可用于治疗早产儿呼吸窘迫综合征(RDS),胎粪吸入综合征(mas)

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