Pharmacological synthesis of mixtures of human insulin Gly (A21) - Arg (B31) Arg (B32) and isopropene-4 (1-39) - lys6-nh2

摘要

It refers to a kind of drug synthesis including insulin and GLP-1 agent, in which insulin is the insulin of Gly (A21) - Arg (B31) - Arg (B32) people, Lys @ b28pro @ B29 human insulin, B28 ASP people's insulin or b29lys (epsilon tetradecanoil), or 30 people's insulin and GLP-1 agent abusers, exendina-4, exendina-3, Among others, there was no 36 exendina-4 (1-39) - lys6-nh2. This component is useful for the treatment of type 1 or type 2 diabetes. It can adjust the concentration of blood glucose in fasting, postpartum and / or posabortiva, improve glucose tolerance, etc.