Used for the production of 5 - (2 - 6 - (2,2-fluoro-2-phenyltosi) hexil) amine} - 1-hydroxy-hydroxy-2 - (1H) - ona

摘要

The preparation procedure of a 5 - (2 - [6 - (2,2-fluoro-2-phenyltosi) hydroxy) amino-1-hydroxy-2 (1H) - Na includes: (a) reacting a formula compound V with 6 - (2,2-fluoro-2-phenyltosi) hexachlorobenzene-1-amino in a solvent such as diene, Where P1 and P2 are protection groups of hydrogen Xi and l, which is a discrete group; (b) perform P1 and P2 protection phases,In order to eliminate the protective population, the above compounds were produced. Through this process, the purification program is changed or even cancelled in some stages, and higher performance and purer way are obtained than before.